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Anesthesia

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Numbing creams for tattoo, permanent makeup and cosmetology: how to choose

Numbing agents for beauty procedures reduce pain and skin sensitivity before tattooing, permanent makeup, mesotherapy, biorevitalisation, laser and wax hair removal. The It's Beauty catalogue has 61 positions: creams, gels, sprays and single-use formats from A-CAINE, B-CAINE, PRO-CAINE, Dr. Numb, F&E Tattooist, GeLido, Frost Line, PM Cream, TKTX, Amor Fati, Klever Safe Touch and others.

Key insight for first-time buyers

The number «10%», «12,5%» or «40%» in a cream's name is the sum of all anaesthetic ingredients, not the lidocaine content. Full breakdowns from manufacturer documents below.

Primary vs secondary anaesthetic: the difference

Primary anaesthetic (cream) is applied to intact skin 10-30 minutes before the procedure under occlusive film. Prevents pain at the first needle insertion.
Examples: A-CAINE 10,95%, B-CAINE 11,5%, PRO-CAINE 12,5%, PM Cream, Amor Fati White Caine.

Secondary anaesthetic (gel) is applied to broken skin during the procedure to maintain numbness while the needle works. Often contains epinephrine (0,02% or 0,1%) to constrict vessels and reduce bleeding.
Examples: Amor Fati Blue Caine, Depain Ice, Sustaine Blue Gel.

Universal works in both scenarios: TKTX Gel 15 ml, GeLido Anestetico.

What «10%», «12,5%» and «40%» really mean on the packaging

For most brands the number in the name is the combined concentration of all anaesthetic ingredients:

A-CAINE 10,95%: lidocaine 5,95% + prilocaine 5%
B-CAINE 11,5%: lidocaine 6,5% + prilocaine 5%
F&E Tattooist 10%: lidocaine 6% + prilocaine 4%
GeLido 10%: lidocaine 7% + prilocaine 2% + benzocaine 1%
Dr. Numb 10%: lidocaine 5% + prilocaine 5% + epinephrine 0,1%
F&E Tattooist Red 7%: lidocaine 5% + tetracaine 2% + epinephrine 0,1%
TKTX «40%»: marketing series label, not lidocaine content. Documented composition of TKTX 15 ml gel: lidocaine 6% + tetracaine 3% + epinephrine 0,2%

Exception: PRO-CAINE 12,5% honest single-lidocaine formula, the only one in the catalogue.

Why combined formulas work faster than mono-lidocaine

Combining lidocaine with prilocaine (or benzocaine, tetracaine) creates synergy: action starts faster and lasts longer than mono-lidocaine at the same total concentration. That's why Korean creams A-CAINE and B-CAINE work in 10-15 minutes, while mono-lidocaine products need 30-45 minutes.

How to choose: matrix by procedure

Procedure Type Examples
Tattoo on intact skin (start) Primary cream A-CAINE, B-CAINE, PM Cream
PMU lips/brows (preparation) Primary cream B-CAINE, White Caine 12,5%
PMU during the session Secondary gel Blue Caine, Depain Ice, TKTX Gel
Mesotherapy, biorevitalisation Primary cream A-CAINE, PRO-CAINE 12,5%
Laser or wax hair removal Primary cream A-CAINE, PM Cream
Lidocaine allergy Lidocaine-free secondary gel Amor Fati Lila Caine

Documents and safety

All numbing products in the It's Beauty catalogue are registered as cosmetics (UKTZED 3304) and passed laboratory safety testing at Ukrainian labs. Product cards reference report numbers and manufacturers: LIDOPHARM, ANESTETPHARM, MISTBIO (South Korea), NUMBINGPHARMA (Canada), F&E Professional (UK), Anestetico laboratorio (Italy), LPC ACTIVIOS (Spain), Klever (Ukraine), Mark Ecopharm (Ukraine).

⚠️ For professional external use only

An allergy patch test is required before first use. Not recommended during pregnancy or breastfeeding. Only secondary gels with epinephrine may be applied to broken skin.

Frequently asked questions

Is it true that TKTX contains 40% lidocaine?
No. «40%» on TKTX packaging is a marketing series label, not lidocaine content. Documented composition of TKTX 15 ml gel: lidocaine 6% + tetracaine 3% + epinephrine 0,2%. TKTX 10 g cream has no manufacturer-confirmed composition, so we don't list percentages on its card.
Which product is the strongest?
Documented highest lidocaine concentration in the catalogue: PRO-CAINE 12,5% (mono-formula). By combined concentration: White Caine «12,5%» (6,5%+5%+1%) and B-CAINE «11,5%» (6,5%+5%) also deliver strong anaesthesia through synergy.
How long does it take to start working?
Combined-formula creams (A-CAINE, B-CAINE, PM Cream): 10-15 minutes under occlusive film. Mono-lidocaine (PRO-CAINE 12,5%, Dr. Gritz Obezbol 10%): 20-30 minutes. Secondary gels work instantly on broken skin.
Which option for clients allergic to lidocaine?
Amor Fati Lila Caine, the only lidocaine-free secondary gel. Uses a proprietary «triodermine» complex plus epinephrine 0,02%. The only option in this category for clients with confirmed lidocaine allergy.
What's the difference between a numbing cream and a gel?
Creams are thick and applied to intact skin before the procedure under occlusive film (primary). Gels are liquid, absorb quickly and are applied to broken skin during the session (secondary). Gels often contain epinephrine to reduce bleeding.